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Cannabidiol (CBD) is a naturally occurring chemical compound found in cannabis. In studying the plant, researchers identified more than 100 such phytochemical compounds that are collectively called cannabinoids, and CBD and tetrahydrocannabinol (THC) are the most prominent in terms of typical volume. CBD does not have psychoactive properties that produce euphoric highs, and it potentially reduces or delays THC-related euphoria. More importantly, clinical studies show that CBD has extensive medical applications, probably more so than any other cannabinoid. Users experience the benefits of CBD with traditional delivery devices, but various extraction methods (e.g., ethanol, olive oil, solvent, grain alcohol, C02) help produce non-psychoactive CBD oils with high potency and measured dosage. The oil concentrate can be smoked, ingested or applied to the skin as a topical cream depending on the medicinal need. How CBD Works Each person has a cannabinoid receptor system in the brain that includes receptor type 1 (CB1) primarily in the central and peripheral nervous system and receptor type 2 (CB2) primarily in the immune system. Whereas THC binds directly to the receptors, CBD affects them indirectly through endocannabinoids produced naturally in the body. In addition to stimulating natural production, CBD suppresses the enzyme that metabolizes endocannabinoids. Though it lacks an affinity for the primary receptors, CBD might increase receptor density and coupling efficiency, and it does bind to other receptors associated with adenosine (A2A), serotonin, pain perception, mood and inflammation, among others. It also appears to deactivate the GPR55 receptor associated with cancer cell proliferation. The cannabinoid receptor system plays an important role in maintaining a stable biological environment, and fittingly, CBD seems to counter potential THC side effects like anxiety, paranoia and short-term memory disruptions. Medical Use of CBD In the medical marijuana (MMJ) field, CBD shows immense promise for a wide range of diseases and disorders, and its non-psychoactive profile allows for practical and inclusive applications. As noted by the Brazilian Journal of Psychiatry in 2008, researchers determined the chemical structure of CBD in 1963, and it sparked an initial wave of medical research into its antiepileptic and sedative properties. These studies, while informative, only captured a glimpse of CBD s medical potential, and renewed research in the new millennium identified antiinflammatory, antioxidant, neuroprotective, analgesic, anxiolytic, antiemetic and neuroleptic properties. Furthermore, Current Drug Safety in 2011 stated that humans tolerate CBD well, even with chronic use and high dosage, and it is nontoxic with no adverse effects related to heart rate, blood pressure, body temperature, food intake, gastrointestinal transit or psychological function. To date, clinical studies involving CBD suggest medical applications for anxiety disorders, schizophrenia, inflammation, diabetes, rheumatoid arthritis, multiple sclerosis, epilepsy, post-traumatic stress disorder (PTSD), opiate addiction, neurodegenerative disorders, heart disease, Parkinson s, Alzheimer s, Crohn s disease and a debilitating form of epilepsy called Dravet s Syndrome. Furthermore, the British Journal of Clinical Pharmacology noted in 2013 that CBD has anticancer properties that interfere with tumor neovascularization, cancer cell migration, adhesion, invasion and metastasization. CBD and THC CBD is appealing for medicinal users since the non-psychoactive oil can be taken in measured, concentrated doses that do not adversely affect cognition or motor skills. Several studies do suggest, however, that CBD reaches optimal efficacy when paired with THC. In addition to boosting the antioxidant potency of CBD, studies show that THC has its own therapeutic profile that includes potential anticancer agents. The two cannabinoids seem to have a symbiotic relationship that fosters mutual enhancement, and some medicinal experts advocate for whole-plant use when appropriate. Still, many individuals prefer the singular use of CBD, especially when the treatment involves children, and the extracted oil is undeniably a potent medicine with or without THC. The immense game-changing potential for CBD-based medical treatments is a primary force driving the cannabis legalization movement.

Cancer-stricken Olivia Newton-John has a new reason to fight, RadarOnline.com has learned exclusively, after daughter Chloe Lattanzi secretly rushed to the altar as a result of her famous mother's horrific diagnosis!

“Seeing her beloved daughter get hitched has given Olivia a reason to live a little longer,” spilled a source. “There’s nothing more she could possibly ask for right now — except maybe a grandchild!”

Lattanzi, 31, started dating James Driskill in 2009, and the two got engaged the following year. But they hadn’t started making wedding plans until 69-year-old Newton-John revealed her devastating stage 4 cancer diagnosis in May.

followed by breast reconstruction, vowing at the time, “I’m going to beat this thing. I have to — for Chloe.”

Chloe — whose father is dancer/actor Matt Lattanzi — was only six at the time.

Miraculously, she saw her mom endure surgery and chemotherapy, and bounce back with a clean bill of health.

tried homegrown marijuana, relying on cannabis oil to ease her pain.

Chloe even reached out to fans, begging for a spiritual lift to save her ailing mom.

“Will all of u send healing prayers for my mom’s back please,” she asked on Instagram.

to brain cancer in 2013.

Although the future looks bleak for Olivia, Chloe’s secret wedding is “the best medicine she could have at this point,” said a close friend.

We pay for juicy info! Do you have a story for RadarOnline.com? Email us at tips@radaronline.com, or call us at 800-344-9598 any time, day or night.

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